Aliskiren improves insulin resistance and ameliorates diabetic vascular complications in db/db mice
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چکیده
منابع مشابه
Ascorbic Acid Improves Vascular Permeability in Experimental-Induced Diabetic Rats
Background: The most devastating manifestations of diabetes mellitus are vascular complications. Although there are many factors involved in the pathogenesis of diabetic vasculopathy, many studies suggest a role for glucose–induced oxidative stress. Studies in animal models, have demonstrated that the administration of antioxidants restores normal endothelial functions. The study was designed t...
متن کاملSargassum coreanum extract alleviates hyperglycemia and improves insulin resistance in db/db diabetic mice
BACKGROUND/OBJECTIVES The goal of this study was to examine the effect of Sargassum coreanum extract (SCE) on blood glucose concentration and insulin resistance in C57BL-KsJ-db/db mice. MATERIALS/METHODS For 6 weeks, male C57BL/KsJ-db/db mice were administrated SCE (0.5%, w/w), and rosiglitazone (0.005%, w/w). RESULTS A supplement of the SCE for 6 weeks induced a significant reduction in bl...
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AIM In this study, we examined the efficacy of whole body hyperthermia (WBH) on obesity-induced insulin resistance in diabetic mice. METHODS Male db/db mice were treated with WBH 3 times per week for 12 weeks. The rectal temperature of mice reached 38.0 degrees C 5 min after heating, and was kept at 38.0 degrees C for 30 min. At the end of each week, tail snip glucose levels were determined u...
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Objective(s): This study was aimed to investigate the effect of Berberis integerrima (B. integerrima) extract on insulin sensitivity in high-fructose-fed insulin-resistant rats. Materials and Methods: Experimental rats were randomly divided into two groups: the control group was fed a regular chow diet while other group fed with a high-fructose diet for 8 weeks. After the first six weeks, the a...
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ژورنال
عنوان ژورنال: Nephrology Dialysis Transplantation
سال: 2010
ISSN: 1460-2385,0931-0509
DOI: 10.1093/ndt/gfq579